| Rank | Title | Weekend |
|---|---|---|
| 1↑ (2) | What Lies Beneath / 2000 | £811,997 |
| 2↓ (1) | Bedazzled / 2000 | £693,858 |
| 3 | Little Nicky / 2000 | £574,337 |
| 4↓ (3) | Pitch Black / 2000 | £541,766 |
| 5↓ (4) | Billy Elliot / 2000 | £527,047 |
| 6↓ (5) | Dinosaur / 2000 | £373,722 |
| 7↔ (7) | The Kid / 2000 | £269,477 |
| 8↔ (8) | The Little Vampire / 2000 | £245,204 |
| 9↓ (6) | Road Trip / 2000 | £240,092 |
| 10↓ (9) | Coyote Ugly / 2000 | £226,097 |
| 11 | The Way of the Gun / 2000 | £191,169 |
| 12↓ (10) | Wonder Boys / 2000 | £102,474 |
| 13 ⇅ (re) | The Cell / 2000 | £96,716 |
| 14 | Duets / 2000 | £92,746 |
| 15↔ (15) | Memento / 2000 | £75,839 |
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