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| Directed by | |
|---|---|
 | Sam Raimi |
| Starring | ||
|---|---|---|
 | Tobey Maguire | Spider-Man / Peter Parker |
| Kirsten Dunst | Mary Jane Watson |
| James Franco | Harry Osborn |
 | Alfred Molina | Doc Ock / Dr. Otto Octavius |
| Rosemary Harris | May Parker |
 | J.K. Simmons | J. Jonah Jameson |
 | Donna Murphy | Rosalie Octavius |
| Daniel Gillies | John Jameson |
| Dylan Baker | Dr. Curt Connors |
| Bill Nunn | Joseph 'Robbie' Robertson |
| Vanessa Ferlito | Louise |
| Aasif Mandvi | Mr. Aziz |
 | Willem Dafoe | Green Goblin / Norman Osborn |
| Cliff Robertson | Ben Parker |
| Ted Raimi | Hoffman |
 | Elizabeth Banks | Miss Brant |
| Bruce Campbell | Snooty Usher |
| Gregg Edelman | Dr. Davis |
| Elya Baskin | Mr. Ditkovich |
| Mageina Tovah | Ursula |
| Daniel Dae Kim | Raymond |
| Hal Sparks | Elevator Passenger |
| Joel McHale | Mr. Jacks |
| Stan Lee | Man Dodging Debris |
| Kelly Connell | Dr. Isaacs |
| Brent Briscoe | Garbage Man |
| Emily Deschanel | Receptionist |
| Jason Fiore-Ortiz | Henry Jackson |
| Scott Spiegel | Man on Balcony |
| Andy Bale | OsCorp Executive |
| Christine Estabrook | Mrs. Jameson |
| Molly Cheek | Society Woman |
| John Paxton | Houseman |
| Joy Bryant | Woman at Web |
| Joanne Baron | Skeptical Scientist |
| Peter McRobbie | OsCorp Representative |
| Timothy Jerome | Injured Scientist |
| Taylor Gilbert | Mrs. Watson |
| Peter Vouras | Stage Manager |
| Donnell Rawlings | Pizza 'Heist' Witness |
| Zachry Rogers | Boy Saved by Spider-Man |
| Ella Rogers | Girl Saved by Spider-Man |
| Louis Lombardi | Poker Player |
| Marc John Jefferies | Amazed Kid |
| Roshon Fegan | Amazed Kid |
| Brendan Patrick Connor | Theater Traffic Cop |
| Reed Diamond | Algernon |
| Dan Callahan | 'Jack' |
| Elyse Dinh | Violinist |
| John Landis | Doctor |
| Tim Storms | Chainsaw Doctor |
| Susie Park | Clawing Nurse |
| Tricia Peters | Screaming Nurse |
| Michael Edward Thomas | Man at Fire |
| Anne Betancourt | Woman at Fire |
| Venus Lam | Child in Burning Building |
| Bill E. Rogers | Fireman |
| Joe Virzi | Fireman |
| Tom Carey | Train Conductor |
| Jopaul Van Epp | Boy with Mask |
| Weston Epp | Boy with Mask |
| Peter Allas | Train Passenger |
| Brianna Brown | Train Passenger |
| Bill Calvert | Train Passenger |
| Tony Campisi | Train Passenger |
| Joey Diaz | Train Passenger |
| Chloe Dykstra | Train Passenger |
| Simone Gordon | Train Passenger |
| Dan Hicks | Train Passenger |
| Julia Max | Train Passenger |
| Savannah Pope | Train Passenger |
| Timothy Patrick Quill | Train Passenger |
| Jill Sayre | Train Passenger |
| Rickey G. Williams | Train Passenger |
| Dakota Anderson | Mugger 1 |
| Sal Ardisi | Parent |
| Michael Arthur | NYPD Officer |
| Damian Bailey | Extra |
| David Blanc | Street Walker |
| Frank Bonsangue | Pizza Man |
| David Boston | Pedestrian |
| Sho Brown | Passenger |
| Luke Burnyeat | Train Passenger |
| Cindy Cheung | Chinese Daughter |
| Peter Cincotti | Piano Player in Planetarium |
| Lee Cogburn | Train Passenger |
| Al Collado | Cab Driver |
| Christina R. Copeland | Chainsaw Nurse |
| Dono Cunningham | Pedestrian |
| Vince Cupone | Victim |
| Barbara Ann Davison | Woman with Dog |
| Calvin Dean | Boomer |
| Fabrizio Fante | Businessman |
| Doug Ferony | Detective |
| Phillip Gramm | NYPD Officer |
| Halla | Wedding Attendee |
| Mohammed Hassan | Middle Eastern Taxi Driver |
| Andre Johnson | Fireman 2 |
| Edward Johnson | Planetarium |
| Michael Kilcullen | Subway Passenger |
| Eileen Kovener | Street Walker |
| Phil La'Marr | Train Passenger |
| Frank Langley | Doc Ock Tentacle Puppeteer |
| Rachel Lehrer | Hot Girl |
 | Peyton List | Little Girl Playing on Steps |
| Spencer List | Little Boy Playing on Steps |
| Lorelei Llee | Bank Employee |
| Fancy Macelli | Reporter |
| Paul-Dean Martin | Bugle Lawyer |
| Carina Mastrippolito | Girl |
| Troy Metcalf | Blue Collar Guy |
| Altara Michelle | Teenage Girl at the Bank |
| Claudia Katz Minnick | Robbie's Assistant |
| Ismael Moreno | Rescued Crosswalker |
| Joseph Nelson | Extra |
| David Orris | Police Officer |
| Ronn Ozuk | Cop |
| Christopher Porto | Man Waiting For Train |
| Sam Raimi | University Student |
| Randy Reinholz | Train Passenger |
| Carla Rhodes | Phone Booth Girl |
| Rachelle Roderick | Jane, Engineer |
| Scott Ross | Pedestrian |
| Bonnie Somerville | Screaming Woman |
| Jimmy Star | Reporter |
| Douglas Swander | Train Passenger |
| Angel Katherine Taormina | Female Onlooker on Street |
| John Thurner | EL Train Passenger |
| Henry Truong | Doc Ock Lab Assistant #2 |
| Michael Urbanski | Man on street |
| Wesley Volcy | Columbia University Student |
| Lou Volpe | Man at Web |
| Garrett Warren | Bearded Doctor |
| Jack Wetherall | Train Passenger |
| Ken Wharton | Uptight Businessman |
Spider-Man 2 is number 13 on the UK box office with £98 Thousand.
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