| Rank | Title | Weekend |
|---|---|---|
| 1 | How the Grinch Stole Christmas / 2000 | £3,063,799 |
| 2↓ (1) | Charlie's Angels / 2000 | £2,250,016 |
| 3↓ (2) | What Lies Beneath / 2000 | £412,013 |
| 4 | Red Planet / 2000 | £330,391 |
| 5 | Urban Legends: Final Cut / 2000 | £265,282 |
| 6↓ (3) | Billy Elliot / 2000 | £241,525 |
| 7 | Small Time Crooks / 2000 | £184,548 |
| 8↓ (4) | Bedazzled / 2000 | £176,367 |
| 9↑ (10) | Coyote Ugly / 2000 | £142,278 |
| 10↓ (6) | Pitch Black / 2000 | £139,927 |
| 11↓ (7) | Dinosaur / 2000 | £95,235 |
| 12↓ (5) | Little Nicky / 2000 | £80,067 |
| 13↓ (11) | The Skulls / 2000 | £70,927 |
| 14↓ (13) | Memento / 2000 | £62,591 |
| 15↓ (8) | The Little Vampire / 2000 | £60,042 |
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