| Rank | Title | Weekend |
|---|---|---|
| 1↔ (1) | How the Grinch Stole Christmas / 2000 | £2,547,769 |
| 2↔ (2) | Charlie's Angels / 2000 | £1,351,638 |
| 3 | 102 Dalmatians / 2000 | £1,179,758 |
| 4↓ (3) | What Lies Beneath / 2000 | £293,886 |
| 5↓ (4) | Red Planet / 2000 | £175,427 |
| 6 | The Art of War / 2000 | £165,830 |
| 7↓ (5) | Urban Legends: Final Cut / 2000 | £164,325 |
| 8↓ (6) | Billy Elliot / 2000 | £137,342 |
| 9↓ (7) | Small Time Crooks / 2000 | £120,806 |
| 10↓ (9) | Coyote Ugly / 2000 | £114,970 |
| 11↓ (8) | Bedazzled / 2000 | £77,715 |
| 12↓ (10) | Pitch Black / 2000 | £53,777 |
| 13↑ (14) | Memento / 2000 | £52,663 |
| 14 | Borstal Boy / 2000 | £33,303 |
| 15↓ (11) | Dinosaur / 2000 | £31,671 |
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