| Rank | Title | Weekend |
|---|---|---|
| 1 | X-Men: Apocalypse / 2016 | £7,354,293 |
| 2↔ (2) | The Angry Birds Movie / 2016 | £2,012,663 |
| 3↔ (3) | The Jungle Book / 2016 | £1,445,165 |
| 4↓ (1) | Captain America: Civil War / 2016 | £1,334,385 |
| 5↓ (4) | Bad Neighbours 2 / 2016 | £766,425 |
| 6 | A Hologram For the King / 2016 | £378,759 |
| 7↓ (5) | Florence Foster Jenkins / 2016 | £243,901 |
| 8↓ (6) | Our Kind of Traitor / 2016 | £211,790 |
| 9↓ (8) | 28 Days Later / 2002 Rerelase | £165,128 |
| 10 | Thomas & Friends: The Great Race / 2016 | £147,617 |
| 11 ⇅ (re) | Sing Street / 2016 | £126,269 |
| 12 | Planeta Singli / 2016 | £95,159 |
| 13↓ (11) | Zootopia / 2016 | £90,595 |
| 14↓ (9) | Eye In the Sky / 2016 | £87,666 |
| 15↓ (7) | Everybody Wants Some!! / 2016 | £71,182 |
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