| Directed by | ||
|---|---|---|
 | Danny DeVito | |
| Starring | ||
|---|---|---|
 | Ben Stiller | Alex Rose |
 | Drew Barrymore | Nancy Kendricks |
| Eileen Essell | Mrs. Connelly |
| Harvey Fierstein | Kenneth |
| Justin Theroux | Coop |
| James Remar | Chick |
| Robert Wisdom | Officer Dan |
| Swoosie Kurtz | Jean |
| Wallace Shawn | Herman |
| Maya Rudolph | Tara |
| Amber Valletta | Celine |
| Cheryl Klein | Ginger |
| Tim Maculan | Terrence |
| Jackie Sandler | Bartender |
| Evgeniy Lazarev | Mr. Dzerzhinsky |
| Kumar Pallana | Indian Restaurant Owner |
| Philip Perlman | Phil |
| Gary Riotto | Drug Dealer |
| Michelle Krusiec | Dr. Kang |
| Margie Loomis | Old Biddy #1 |
| Linda Porter | Old Biddy #2 |
| Edward Edwards | Antique Dealer |
| Louis Giambalvo | Pharmacist |
| Tracey Walter | Pharmacy Customer |
| John Hamburg | Mr. Friedman |
| Christina Kirk | Mrs. Friedman |
| Jenette Goldstein | Moderator |
| Leyna Nguyen | Female Newscaster |
| Chuma Gault | Mailroom Guy |
| Jim Castillo | Weatherman |
| Michael Fahn | Sneezer on Train |
| Roberta R. Deen | Caterer |
| Christopher Doyle | Tavern Bartender |
| Christine La Fontaine | Don Piper Fan #1 |
| Joey Banks | Police Officer |
| Geraldine Hughes | Receptionist |
| Picasso | Little Dick |
| Guiles | Little Dick |
| Bugsy | Little Dick |
| Maestro | Little Dick |
| Will Blomquist | College Student on Subway |
| Danny DeVito | Narrator |
| Larry Vigus | Man on the Street |
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