| Rank | Title | Weekend |
|---|---|---|
| 1 | Doctor Strange / 2016 | £9,288,898 |
| 2↓ (1) | Trolls / 2016 | £3,256,912 |
| 3↓ (2) | Jack Reacher Never Go Back / 2016 | £1,258,900 |
| 4↓ (3) | The Girl On the Train / 2016 | £1,215,472 |
| 5↑ (8) | Storks / 2016 | £736,177 |
| 6↓ (5) | Bridget Jones's Baby / 2016 | £673,069 |
| 7↓ (4) | Inferno / 2016 | £648,287 |
| 8 | Ae Dil Hai Mushkil / 2016 | £617,400 |
| 9↓ (7) | Miss Peregrines Home For Peculiar Children / 2016 | £549,103 |
| 10↓ (6) | Ouija: Origin of Evil / 2016 | £532,375 |
| 11↓ (9) | I, Daniel Blake / 2016 | £476,020 |
| 12↑ (13) | The Secret Life of Pets / 2016 | £139,642 |
| 13↓ (10) | Keeping Up With the Joneses / 2016 | £80,635 |
| 14↑ (15) | The BFG / 2016 | £72,086 |
| 15↓ (14) | Finding Dory / 2016 | £70,909 |
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